Mouse Anti-Bacitracin (BCT) Monoclonal Antibody

Bacitracin is a polypeptide antibiotic that targets the bacterial cell wall synthesis. It specifically inhibits the dephosphorylation of the lipid carrier undecaprenyl pyrophosphate, which is essential for the transport of peptidoglycan subunits across the cell membrane. By disrupting this process, bacitracin prevents the cross-linking of peptidoglycan chains, weakening the cell wall and leading to bacterial cell death. Bacitracin is effective against a wide range of Gram-positive bacteria, making it a valuable tool in treating skin infections. Its specific interaction with the cell wall synthesis pathway makes it a relevant target for antibody development to enhance detection and monitoring in clinical and research settings, supporting effective treatment and management of bacterial infections.