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Mouse Angiotensin I Converting Enzyme 2 (ACE2) ELISA Kit-Sandwich

Cat. No.EK5F690

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Angiotensin I Converting Enzyme 2 (ACE2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ACE2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Angiotensin I Converting Enzyme 2 (ACE2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 12.5-800 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Angiotensin-converting enzyme 2 (ACE2) is a vital counter-regulatory carboxypeptidase within the renin-angiotensin hormone system, playing a critical role in regulating blood volume, systemic vascular resistance, and thus maintaining cardiovascular homeostasis. It converts angiotensin I into angiotensin 1-9, a peptide with anti-hypertrophic effects on cardiomyocytes, and angiotensin II into angiotensin 1-7, which serves as a beneficial vasodilator and anti-proliferative agent, counteracting the effects of the vasoconstrictor angiotensin II. In mice, ACE2 has a variety of physiological functions, including blood pressure regulation, kidney protection, anti-inflammatory and antioxidant effects, immune modulation, and metabolic regulation.

Target/Biomarker Mouse ACE2
Target Synonym ACEH; ACEII; ACE-II; Peptidyl-Dipeptidase A; ACE-related carboxypeptidase; Angiotensin-converting enzyme homolog; Metalloprotease MPROT15
Gene ID 70008
UniProt ID Q8R0I0

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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