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Mouse Alpha-Tocopherol Transfer Protein (TTPa) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Alpha-Tocopherol Transfer Protein (TTPa) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TTPa in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Alpha-tocopherol transfer protein binds to alpha-tocopherol, facilitating its transfer between membranes and promoting its release from liver cells. This protein can bind to both phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 4,5-bisphosphate, inducing a conformational change crucial for the release of bound alpha-tocopherol. In alpha-TTP knockout mice (Ttpa-/-), there is a severe deficiency of vitamin E, particularly in the brain, liver, and other peripheral tissues. This deficiency can lead to various physiological issues, including neurodegenerative diseases and reproductive disorders. α-TTP-deficient mice exhibit severe α-tocopherol deficiency in multiple brain regions, which is closely associated with neurological dysfunction.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.