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Mouse Agouti Related Protein (AGRP) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Agouti Related Protein (AGRP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse AGRP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Agouti-related protein (AGRP) is crucial in maintaining weight homeostasis and controlling feeding behavior via the central melanocortin system. It functions as an antagonist to alpha melanocyte-stimulating hormone by inhibiting cAMP production, which is mediated by the stimulation of melanocortin receptors in the hypothalamus and adrenal gland. In mice, AGRP is vital for energy balance and metabolic regulation by opposing melanopsin receptor signaling, regulating appetite and energy intake, and interacting with other hormones and neuropeptides. AGRP expression is often elevated in mouse models of obesity and diabetes; for instance, in ob/ob mice, its expression levels are approximately 8-fold higher than in wild-type mice, resulting in significant obesity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.