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Mouse Adenosine Kinase (ADK) ELISA Kit-Sandwich

Cat. No.EK6F465

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Adenosine Kinase (ADK) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ADK in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Adenosine Kinase (ADK).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Adenosine kinase catalyzes the ATP-dependent phosphorylation of the purine nucleoside adenosine at the 5' position, acting as a potential regulator of extracellular adenosine and intracellular adenine nucleotide concentrations. Predominantly expressed in astrocytes in the mouse brain, ADK plays a vital role in maintaining nervous system homeostasis by regulating adenosine levels. Overexpression of ADK can lower brain adenosine levels, leading to learning and memory disorders, epileptic seizures, and neuronal damage. In epilepsy models, increased ADK is closely linked to astrocyte overactivation and neuronal dysfunction in the hippocampus. Inhibiting ADK activity can help reduce epileptic seizures.

Target/Biomarker Mouse ADK
Target Synonym AK; Adenosine 5'-Phosphotransferase
Gene ID 11534
UniProt ID P55264

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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