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Mouse Adenosine A2b Receptor (ADORA2b) ELISA Kit-Sandwich

Cat. No.EK6F430

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Adenosine A2b Receptor (ADORA2b) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ADORA2b in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Adenosine A2b Receptor (ADORA2b).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Adenosine receptor A2b is a receptor that responds to adenosine, with its activity being mediated by G proteins that activate adenylyl cyclase. In a mouse model of lung inflammation triggered by lipopolysaccharide (LPS), mice lacking Adora2b were unable to increase Treg cell levels, leading to more severe inflammation and greater cell infiltration. In a myocardial ischemia model, agonists targeting Adora2b significantly reduced the size of myocardial infarctions and decreased cardiac injury marker levels. Moreover, Adora2b enhanced cardioprotection by modulating myeloid cell (such as macrophages) signal transduction.

Target/Biomarker Mouse ADORA2b
Target Synonym ADORA2B; Adenosine receptor A2b
Gene ID 11541
UniProt ID Q60614

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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