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Mouse Activated Protein C (APC) ELISA Kit-Sandwich

Cat. No.EK5F586

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Activated Protein C (APC) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse APC in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Activated Protein C (APC).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

In mice, activated protein C (APC) plays significant roles in anticoagulation, protecting vascular barriers, and regulating inflammatory responses. APC functions as an anticoagulant protease by binding to protein C receptors (such as protein C receptor-1, EPCR) and activating protease-activated receptor-1 (PAR1). This mechanism has been validated in mouse models. For instance, studies have demonstrated that APC can maintain the integrity of the vascular barrier by enhancing endothelial cell barrier function and reducing vascular permeability. Beyond its anticoagulation properties, APC in mice is also involved in protecting vascular barriers, modulating inflammatory responses, and playing crucial roles in various disease models.

Target/Biomarker Mouse APC
Target Synonym APC

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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