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Mouse A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse A Disintegrin And Metalloprotease 8 (ADAM8) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ADAM8 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Disintegrin and metalloproteinase domain-containing protein 8 (ADAM8) may play a role in the extravasation of leukocytes. In mice, ADAM8 has a wide range of functions, impacting areas such as neurodegenerative diseases, immune and inflammatory responses, tumor progression, tissue remodeling, and bone metabolism. It is particularly significant in neurodegenerative diseases; in the Wobbler mouse model, ADAM8 expression is linked to neuron-glial cell interactions and may influence the development of neurodegenerative lesions by regulating cell adhesion. Additionally, ADAM8 exhibits potential therapeutic value in a mouse spinal cord injury model by modulating endogenous inflammatory responses and enhancing neuroprotection.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Qian, Zhanyang et al. "Blockade of the ADAM8-Fra-1 complex attenuates neuroinflammation by suppressing the Map3k4/MAPKs axis after spinal cord injury." Cellular & molecular biology letters vol. 29,1 75. 16 May. 2024.