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Immortalized Mouse Kupffer Cells

Product Overview

Hepatic Kupffer cells, located within the hepatic sinusoidal lumen, possess amoeboid movement and active phagocytic function. They also play a role in processing and transmitting antigens and regulating the body's immune response, and are key members of the mononuclear phagocytic system. They are important defensive cells that clear bacteria and their toxins to antagonize infection, and also play a leading role in the development of endotoxin-induced liver injury by releasing various inflammatory mediators. Immortalized mouse Kupffer cells have been validated through 30 consecutive passages; these cells have been identified using a specific marker (CD163).

Specifications

Cell Product Type Primary Cells-Immortalized

Species Mouse

Cell Type Kupffer Cells

Source Normal Liver Tissue

Growth Information Adherent; 37°C; 5%CO₂

Quality Control Mycoplasma (-); Bacteria (-); Yeast (-); Fungi (-)

Physical State Frozen cells

Shipping and Storage

This product is shipped with dry ice. It's recommended to store the product with liquid nitrogen and never in a -20 °C or -80 °C refrigerator. Avoid repeated freezing and thawing of the product.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.