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Guinea Pig Transforming Growth Factor Beta 1 (TGFB1) ELISA Kit-Sandwich
Product Overview
BioVenic Guinea Pig Transforming Growth Factor Beta 1 (TGFB1) ELISA Kit-Sandwich is designed for the quantitative determination of Guinea Pig TGFB1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Transforming growth factor beta 1 (TGF-β1) is a polypeptide belonging to the transforming growth factor beta superfamily of cytokines. This secreted protein has diverse cellular functions and plays a crucial role in regulating the immune system, exhibiting varied effects on different cell types or cells at various developmental stages. Most immune cells, or leukocytes, secrete TGF-β1. Additionally, TGF-β1 differentially regulates the expression of integrin subunits in guinea pig airway epithelial cells. Guinea pigs are extensively used as models for respiratory diseases, particularly asthma and airway remodeling. TGF-β1's role in airway fibrosis and smooth muscle remodeling has been investigated in guinea pig models.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Sheppard, D., et al. "Transforming growth factor beta differentially regulates expression of integrin subunits in guinea pig airway epithelial cells."Journal of Biological Chemistry 267.24 (1992): 17409-17414.; Oenema, Tjitske A et al. "Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices." PloS one vol. 8,6 e65580. 26 Jun. 2013.