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Guinea Pig Matrix Metalloproteinase 13 (MMP13) ELISA Kit-Sandwich

Cat. No.EK3F98

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Guinea Pig Matrix Metalloproteinase 13 (MMP13) ELISA Kit-Sandwich is designed for the quantitative determination of Guinea Pig MMP13 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Guinea Pig MMP13.
Target Species Guinea Pig
Species Reactivity Guinea Pig
Detection Range 31.3-2000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

In Guinea pigs, collagenase 3 is encoded by the MMP13 gene. Matrix metalloproteinase-13 (MMP-13) is the main enzyme responsible for cartilage degradation, primarily due to its unique ability to cleave type II collagen. As a key enzyme, collagenase 3 is crucial for the cleavage of type II collagen and significantly contributes to the breakdown of cartilage in osteoarthritic joints. Guinea pigs can be used as models for osteoarthritis, and MMP13's role in cartilage degradation is investigated. Guinea pigs can also be used in wound healing studies, and MMP13's role in collagen degradation and tissue remodeling is investigated.

Target/Biomarker Guinea Pig MMP13
Target Synonym MMP-13; Matrix Metalloproteinase 13; MMP13
Gene ID 100731756

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Hu, Qichan, and Melanie Ecker. "Overview of MMP-13 as a Promising Target for the Treatment of Osteoarthritis." International journal of molecular sciences vol. 22,4 1742. 9 Feb. 2021.
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