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Guinea Pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit-Sandwich

Cat. No.EK3F86

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Guinea Pig Brain Derived Neurotrophic Factor (BDNF) ELISA Kit-Sandwich is designed for the quantitative determination of Guinea Pig BDNF in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Guinea Pig BDNF.
Target Species Guinea Pig
Species Reactivity Guinea Pig
Detection Range 0.16-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Brain-derived neurotrophic factor (BDNF) belongs to the neurotrophin family of growth factors, related to the well-known nerve growth factor (NGF) family, which also comprises NT-3 and NT-4/NT-5. BDNF targets specific neurons in both the central and peripheral nervous systems that express the TrkB receptor, aiding in the survival of existing neurons while promoting the growth and differentiation of new neurons and synapses. Studies suggest that a combined treatment of BDNF and neurotrophin-3 is more effective than either alone in preserving the auditory nerve in deafened guinea pigs.

Target/Biomarker Guinea Pig BDNF
Target Synonym Neurotrophin; Abrineurin; Brain-derived neurotrophic factor; BDNF
Gene ID 100730257
UniProt ID O70183

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Vink, Henk A et al. "Combined brain-derived neurotrophic factor and neurotrophin-3 treatment is preferred over either one separately in the preservation of the auditory nerve in deafened guinea pigs." Frontiers in molecular neuroscience vol. 15 935111. 26 Sep. 2022.
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