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Guinea Pig Anti-Rabbit Complement Component 9 (C9) Polyclonal Antibody
Product Overview
BioVenic guinea pig polyclonal antibody is specific for rabbit complement component 9. It is purified by protein A/G. It can be applied to WB and IHC assays of rabbit complement component 9.
Specifications
Target Information
Rabbit complement component 9 (C9) is a 63 kDa single-chain glycoprotein whose N-terminal thrombospondin domain and C-terminal membrane-inserting β-barrel polymerize into the terminal complement complex, forming transmembrane pores. A solvent-exposed 16-aa "KVE" loop (aa 285-300) between the LDLRA module and the membrane attack domain folds into a β-hairpin unique among rabbit complement proteins, presenting a conformational epitope preserved after polymerization and fixation. Affinity-purified antibodies targeting this loop trace native C9 in serum, glomerular capillaries, and choroid plexus, delivering crisp extracellular rings and single-band clarity on immunoblots with no cross-reaction to C8 or other terminal complement components.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.