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Guinea Pig Anti-Rabbit Collagen Type II Alpha 1 (COL2a1) Polyclonal Antibody
Product Overview
BioVenic guinea pig polyclonal antibody is specific for rabbit collagen type II alpha 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rabbit collagen type II alpha 1.
Specifications
Target Information
Rabbit collagen type II alpha 1 (COL2A1) is a fibrillar collagen protein encoded by the Col2a1 gene in Oryctolagus cuniculus, mapped to chromosome 1. It belongs to the fibrillar collagen family, featuring conserved Gly-X-Y triple helix repeats, N-terminal propeptide and C-terminal telopeptide critical for fibril assembly. It localizes primarily to extracellular matrix, with tissue-specific expression in rabbit articular cartilage, hyaline cartilage and intervertebral disc, with no expression in skin or bone tissues. The protein forms homotrimeric collagen fibrils, with conserved motifs for cross-linking and structural integrity. Rabbit COL2A1 shares core functional domains with mammalian orthologs, and has distinct fibril density features differentiating it from COL1A1 and other fibrillar collagen isoforms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.