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Guinea Pig Anti-Rabbit ATPase Na+/K+ Transporting Alpha 1 Polypeptide (ATP1a1) Polyclonal Antibody
Product Overview
BioVenic guinea pig polyclonal antibody is specific for rabbit ATPase, Na+/K+ transporting alpha 1 polypeptide. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rabbit ATPase, Na+/K+ transporting alpha 1 polypeptide.
Specifications
Target Information
Rabbit ATPase, Na⁺/K⁺ transporting alpha 1 polypeptide (ATP1A1) is a 1,016-residue transmembrane enzyme forming the catalytic core of the sodium-potassium pump. Its N-terminal cytoplasmic tail anchors ankyrin, the M1-M10 helices create cation pathways, and the large M4-M5 loop houses the ATP phosphorylation site (Asp376). Expressed ubiquitously in kidney, brain and skeletal muscle, the pump cycles between E1- and E2-phospho intermediates to exchange three Na⁺ for two K⁺. Antibodies raised against the M4-M5 loop or C-terminal peptide detect native α1 with negligible cross-reactivity to α2 or α3 isoforms, enabling precise immunoblot and immunohistochemical localization in rabbit tissue homogenates and sections.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.