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Guinea Pig Anti-Rabbit Aquaporin 1 (AQP1) Polyclonal Antibody
Product Overview
BioVenic guinea pig polyclonal antibody is specific for rabbit aquaporin 1. It is purified by protein A/G. It can be applied to WB, IHC, ICC and IP assays of rabbit aquaporin 1.
Specifications
Target Information
Rabbit aquaporin 1 (AQP1) is a transmembrane channel protein of the major intrinsic protein family, a core mediator of rapid water transport across cell membranes. It features six conserved hydrophobic transmembrane domains, two asparagine-proline-alanine motifs critical for pore formation, and cytoplasmic N- and C-terminal regions for structural stability. It localizes predominantly to the plasma membrane of rabbit erythrocytes, renal proximal tubule cells and vascular endothelial cells, with negligible expression in water-impermeable cell types. The protein mediates osmotic water flux via its homotetrameric configuration, with conserved structural motifs differentiating it from AQP2 and AQP4 isoforms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.