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Equine Histamine Receptor H4 (HRH4) ELISA Kit-Sandwich

Cat. No.EK1F97

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Equine Histamine Receptor H4 (HRH4) ELISA Kit-Sandwich is designed for the quantitative determination of Equine Histamine Receptor H4 (HRH4) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Equine HRH4. No cross-reactivity with other relevant proteins.
Target Species Equine
Species Reactivity Equine
Detection Range 0.16-10 ng/mL
Sensitivity 0.051 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 210 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

The Histamine H4 receptor (H4R), like the other three histamine receptors, belongs to the G protein-coupled receptor superfamily. It plays a vital role in immune regulation and has diverse functions. Histamine Receptor H4 is encoded by the HRH4 gene in horses. It is a receptor correlated with inflammatory dendritic epithelial cells. Research has shown that HRH4 is significantly upregulated in lesional whole skin of insect bite hypersensitivity horses.

Target/Biomarker Equine HRH4
Target Synonym GPCR105; GPRv53; H4R; HH4R; H4; AXOR35; BG26; G-protein coupled receptor 105
Gene ID 100034111

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Cvitas, I. et al. Investigating the epithelial barrier and immune signatures in the pathogenesis of equine insect bite hypersensitivity. PloS one. 2020, 15: e0232189.
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