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Canine Beta-secretase 1 (BACE1) ELISA Kit-Sandwich

Name: Canine Beta-secretase 1 (BACE1) ELISA Kit-Sandwich
SKU: EK11F154
Rating: 5 (1 reviews)

Cat. No.EK11F154

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Canine BACE1 ELISA Kit-Sandwich is designed for the quantitative determination of Canine BACE1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Canine BACE1.

Target Species Canine

Species Reactivity Canine

Detection Range 56-3200 pg/mL

Sensitivity 15 pg/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 180 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids;10 μL

Target Information

Beta-secretase 1 is encoded by the AOC1 gene in dogs. BACE1 is a key protease controlling the formation of amyloid β, a peptide hypothesized to play a significant role in the pathogenesis of Alzheimer's disease (AD).

Target/Biomarker Canine BACE1

Target Synonym beta-secretase 1; ASP2; aspartyl protease 2; beta-site APP-cleaving enzyme 1; beta-site amyloid precursor protein cleaving enzyme 1; membrane-associated aspartic protease 2

Gene ID 489390

UniProt ID A0A8I3MSU1

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

May, P. C. et al. The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2015, 35: 1199-1210.