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Bovine Rho Family GTPase 1 (RND1) ELISA Kit-Sandwich

Cat. No.EK12F73

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Bovine Rho family GTPase 1 (RND1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Rho-Related GTP-Binding Protein Rho6 (RND1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine RND1.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Rho family GTPase 1, also known as RhoA, is a member of the Rho family of small GTPases. It is an important regulator of various cellular processes, including actin cytoskeleton organization, cell migration, cell adhesion, and cell proliferation. Bovine Rho family GTPase 1 is encoded by the RND1 gene in cattle. RND1 gene upregulation is associated with cell rounding due to its inhibition of actin stress fibre formation and loss of integrin-based focal adhesions. It may play a pathogenic role in bovine foot skin tissues with acute Bovine digital dermatitis lesions.

Target/Biomarker Bovine RND1
Target Synonym Rho family GTPase 1; rho-related GTP-binding protein Rho6
Gene ID 508869
UniProt ID Q2HJ68

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Newbrook, K. et al. Challenge of Bovine Foot Skin Fibroblasts With Digital Dermatitis Treponemes Identifies Distinct Pathogenic Mechanisms. Frontiers in cellular and infection microbiology. 2021, 10.
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