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Bovine Letm1 Domain-Containing Protein 1 (LETMD1) ELISA Kit-Sandwich

Name: Bovine Letm1 Domain-Containing Protein 1 (LETMD1) ELISA Kit-Sandwich
SKU: EK11F722
Rating: 5 (1 reviews)

Cat. No.EK11F722

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Letm1 Domain-Containing Protein 1 (LETMD1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Letm1 Domain-Containing Protein 1 (LETMD1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine LETMD1.

Target Species Bovine

Species Reactivity Bovine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine LETM1 domain-containing protein 1 is encoded by the LETMD1 gene in cattle. It is a brown adipose tissue (BAT)-enriched and cold-induced protein required for cold-stimulated respiration and BAT thermogenesis. It plays an essential role in mitochondrial structure and function and thermogenesis of brown adipocytes. In brown adipose tissue, it also localises to the nucleus where it interacts with the chromatin remodeler SMARCA4 to regulate the expression of thermogenic genes such as UCP1.

Target/Biomarker Bovine LETMD1

Target Synonym LETM1 domain containing 1; LETM1 domain-containing protein 1

Gene ID 514595

UniProt ID A3KN46

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Park, A. et al. Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nature communications. 2023, 14: 3746.