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Bovine Probable 4-Hydroxy-2-Oxoglutarate Aldolase, Mitochondrial (HOGA1) ELISA Kit-Sandwich

Name: Bovine Probable 4-Hydroxy-2-Oxoglutarate Aldolase, Mitochondrial (HOGA1) ELISA Kit-Sandwich
SKU: EK12F283
Rating: 5 (1 reviews)

Cat. No.EK12F283

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Probable 4-Hydroxy-2-Oxoglutarate Aldolase, Mitochondrial (HOGA1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Probable 4-Hydroxy-2-Oxoglutarate Aldolase, Mitochondrial (HOGA1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine HOGA1.

Target Species Bovine

Species Reactivity Bovine

Detection Range 0.78-50 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Bovine Probable 4-Hydroxy-2-Oxoglutarate Aldolase, Mitochondrial is encoded by the HOGA1 gene in cattle. It is a mitochondrial enzyme that plays a gatekeeper role in hydroxyproline metabolism. HOGA1 catalyzes the final step in the metabolic pathway of hydroxyproline. Specifically, it converts 4-hydroxy-2-oxoglutarate into glyoxylate and pyruvate. This enzymatic reaction occurs within the mitochondrial matrix. Loss of function mutations in the HOGA1 gene can lead to primary hyperoxaluria type 3 (PH3).

Target/Biomarker Bovine HOGA1

Target Synonym 4-hydroxy-2-oxoglutarate aldolase 1; NPL2; DHDPSL; C10orf65; 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; DHDPS-like protein; N-acetylneuraminate pyruvate lyase 2 (putative); dihydrodipicolinate synthase-like, mitochondrial; probable 2-keto-4-hydroxyglutarate aldolase; probable 4-hydroxy-2-oxoglutarate aldolase, mitochondrial; probable KHG-aldolase

Gene ID 506001

UniProt ID Q0P5I5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.