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Bovine Exostosin-1 (EXT1) ELISA Kit-Sandwich

Cat. No.EK2F381

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Exostosin-1 (EXT1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Exostosin-1 (EXT1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Bovine EXT1.
Target Species Bovine
Species Reactivity Bovine
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 210 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Exostoxin 1 (EXT1) is a type II transmembrane glycoprotein located in the endoplasmic reticulum (ER). EXT1 is one of two endoplasmic reticulum-resident type II transmembrane glycosyltransferases, the other being EXT2. These enzymes play a crucial role in the chain elongation step of heparan sulfate biosynthesis. It may be a promising novel target to overcome cancer cell stemness in anthracycline-based therapeutic resistance.

Target/Biomarker Bovine EXT1
Target Synonym Exostosin-1; EC 2.4.1.225; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase
Gene ID 538602
UniProt ID A5D7I4

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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References

  1. Manandhar, S. et al. Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells. Oncotarget. 2017, 8: 70521-70537.
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